"Pardon me, don't mean to bother you, but I've just quit smoking, would you mind blowing some of that in my direction?"

The lady in question, if she indulges you at all, may not only do so once, but a number of times.

And depending on how much she's had to drink, it may lead to other things.

On the subject of pick-up lines, again, not that I've had any personal experience, I'd go for…

Buy you a drink?

It's pretty safe, but given the choice, I'd rather not look like a tool.

But that said, with my looks, I'd probably end up wearing whatever she's drinking.

And with my luck, I'd target the one babe who is there with her Husband, and he's just come back from the loo.